Cat#:PA-2561F;Product Name:Rabbit Anti-Human Chorionic Gonadotropin Antibody;Synonym:Anterior pituitary glycoprotein hormones common subunit alpha; CG alpha; CG-alpha; CGA; Choriogonadotropin Alpha Chain; Chorionic Gonadotrophin Alpha Subunit; Chorionic gonadotrophin subunit alpha; Chorionic gonadotropin alpha polypeptide; Follicle Stimulating Hormone Alpha Chain; Follicle-stimulating hormone alpha chain; Follitropin Alpha Chai; FSH Alpha; FSH-alpha; FSHA; GLHA_HUMAN; Glycoprotein hormones alpha chain; Glycoprotein Hormones Alpha Polypeptide; GPH Alpha; GPHa; GPHA1; HCG; LHA; LSH alpha; LSH-alpha; Luteinizing Hormone Alpha Chain; Lutropin Alpha Chain; Thyroid Stimulating Hormone Alpha Chain; Thyroid-stimulating hormone alpha chain; Thyrotropin Alpha Chain; TSH Alph; TSH-alpha; TSHA;Background:hCG is a 40 kDa glycoprotein composed of two subunits, α and β. The α subunit is common for hCG, LH, follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH), while the β subunit is unique for hCG although its amino acid sequence partially is identical with that of the β subunit of LH. hCG is the most important marker of gestational trophoblastic cells, being present in syncytiotrophoblastic cells and cells of the intermediate trophoblast but absent in cytotrophoblasts. hCG expression has also been demonstrated in some non-trophoblastic tumours, e.g. in 14% of patients with hepatocellular carcinoma. In pregnancy, the serum hCG concentration increases at an exponential rate initially, then peaks at around 100 kIU/L at about the tenth week after conception. The concentration decreases about tenfold over the next several weeks followed by a small increase near term.;Description:Rabbit Anti-Human Chorionic Gonadotropin Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Isotype:IgG1, kappa;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
hCG is a 40 kDa glycoprotein composed of two subunits, α and β. The α subunit is common for hCG, LH, follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH), while the β subunit is unique for hCG although its amino acid sequence partially is identical with that of the β subunit of LH. hCG is the most important marker of gestational trophoblastic cells, being present in syncytiotrophoblastic cells and cells of the intermediate trophoblast but absent in cytotrophoblasts. hCG expression has also been demonstrated in some non-trophoblastic tumours, e.g. in 14% of patients with hepatocellular carcinoma. In pregnancy, the serum hCG concentration increases at an exponential rate initially, then peaks at around 100 kIU/L at about the tenth week after conception. The concentration decreases about tenfold over the next several weeks followed by a small increase near term.