Cat#:PA-3656F;Product Name:Rabbit Anti-Human CCL5 Antibody;Synonym:CCL5; chemokine (C-C motif) ligand 5; SISd; SCYA5; RANTES; TCP228; D17S136E; MGC17164; small inducible cytokine A5 (RANTES); beta-chemokine RANTES; regulated upon activation, normally T-expressed, and presumably secreted; SIS-delta; small inducible cytokine subfamily A (Cys-Cys), member 5; T-cell specific protein p288; T-cell specific RANTES protein; C-C motif chemokine 5; EoCP; Eosinophil chemotactic cytokine; Small-inducible cytokine A5; T cell-specific protein P228; T-cell-specific protein RANTES; RANTES(3-68); RANTES(4-68); C-C motif chemokine 5; eoCP; OTTHUMP00000163880; OTTHUMP00000197106; beta-chemokine RANTES; small-inducible cytokine A5; t cell-specific protein P228; eosinophil chemotactic cytokine;Background:It is also known as RANTES (Regulated upon Activation, Normal T-cell Expressed, and Secreted). CCL5 is an 8kDa protein classified as a chemotactic cytokine or chemokine. CCL5 is chemotactic for T cells, eosinophils, and basophils, and plays an active role in recruiting leukocytes into inflammatory sites. With the help of particular cytokines (i.e., IL-2 and IFN-γ) that are released by T cells, CCL5 also induces the proliferation and activation of certain natural-killer (NK) cells to form CHAK (CC-Chemokine-activated killer) cells.[2] It is also an HIV-suppressive factor released from CD8+ T cells. This chemokine has been localized to chromosome 17 in humans. RANTES was first identified in a search for genes expressed late (3–5 days) after T cell activation. It was subsequently determined to be a CC chemokine and expressed in more than 100 human diseases. RANTES expression is regulated in T lymphocytes by Kruppel like factor 13 (KLF13). RANTES, along with the related chemokines MIP-1alpha and MIP-1beta, has been identified as a natural HIV-suppressive factor secreted by activated CD8+ T cells and other immune cells.;Description:Rabbit Anti-Human CCL5 Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Application:ELISA, Neut, WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;