Cat#:PA-3682F;Product Name:Rabbit Anti-Human CASP4 (N-terminal) Antibody;Synonym:Apoptosis related cysteine peptidase; Apoptotic cysteine protease Mih1/TX; CASP 4; CASP-4; CASP4; CASP4_HUMAN; Caspase-4 subunit 2; Caspase4; ICE(rel) II; ICE(rel)-II; ICE(rel)II; ICEREL II; ICERELII; ICH 2; ICH 2; Mih1/TX; Protease ICH-2; Protease TX; TX; TX protease; OTTHUMP00000231863; OTTHUMP00000231864; caspase 4, apoptosis-related cysteine protease; EC 3.4.22.57; EC 3.4.22;Background:This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.;Description:Rabbit Anti-Human CASP4 (N-terminal) Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Application:IHC, WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;