Cat#:PA-3687F;Product Name:Rabbit Anti-Human CASP2 (N-terminal) Antibody;Synonym:Apoptosis related cysteine peptidase; CASP 2; Casp 2L Pro; CASP2; Caspase 2 apoptosis related cysteine protease; Caspase2; Developmentally down regulated 2; ICH 1; ICH 1 protease; ICH 1L; ICH 1L/1S; ICH1; ICH1 protease; ICH1L/1S; NEDD 2; NEDD2 apoptosis regulatory gene; Neural precursor cell expressed; Neural precursor cell expressed developmentally down regulated 2; OTTHUMP00000025259; OTTHUMP00000202227; neural precursor cell expressed developmentally down-regulated protein 2; EC 3.4.22.55; Protease ICH-1;Background:This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.;Description:Rabbit Anti-Human CASP2 (N-terminal) Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Isotype:IgG1;Application:WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;