Cat#:PA-3689F;Product Name:Rabbit Anti-Human CASP12 Antibody;Synonym:CASP12; UNQ9415; Apoptosis related cysteine protease; CASP 12; CASP-12; casp12; CASP12P1; Caspase 12 pseudogene 1; Caspase12; CASPC_HUMAN; Inactive caspase-12; inactive caspase-12-like; EC 3.4.22;Background:The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation.;Description:Rabbit Anti-Human CASP12 Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Isotype:IgG1;Application:IHC, WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation.
Description:
Rabbit Anti-Human CASP12 Polyclonal Antibody
Host Species:
Rabbit
Species Reactivity:
Human
Isotype:
IgG1
Application:
IHC, WB
Usage:
For Lab Research Use Only
Storage:
Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles