Cat#:PA-4060F;Product Name:Rabbit Anti-Human ANAPC11 (C-terminal) Antibody;Synonym:ANAPC11; anaphase promoting complex subunit 11; APC11; Apc11p; MGC882; HSPC214; Anaphase-promoting complex subunit 11; Cyclosome subunit 11; Hepatocellular carcinoma-associated RING finger protein; anaphase-promoting complex subunit 11; cyclosome subunit 11; APC11 anaphase promoting complex subunit 11 homolog; hepatocellular carcinoma-associated RING finger protein; anaphase promoting complex subunit 11 (yeast APC11 homolog);Background:Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.;Description:Rabbit Anti-Human ANAPC11 (C-terminal) Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Isotype:IgG2b;Application:ELISA, IP, WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.