Cat#:PA-4195F;Product Name:Rabbit Anti-Human ADAMTS5(N-terminal) Antibody;Synonym:ADAMTS5; FLJ36738; ADAMTS11; A Disintigrin And Metalloproteinase with Thrombospondin motif-5; A Disintigrin And Metalloproteinase with Thrombospondin motif-5 (ADAMTS-5), (Aggrecanase-2), Aminoterminal end; ADAMTS-5 (N-terminal);Background:This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage;Description:Rabbit Anti-Human ADAMTS5(N-terminal) Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Isotype:IgG1;Application:WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
ADAMTS5; FLJ36738; ADAMTS11; A Disintigrin And Metalloproteinase with Thrombospondin motif-5; A Disintigrin And Metalloproteinase with Thrombospondin motif-5 (ADAMTS-5), (Aggrecanase-2), Aminoterminal end; ADAMTS-5 (N-terminal)
Gene Introduction:
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage