Cat#:PA-3355F;Product Name:Rabbit Anti-Bovine Collagen I Antibody;Synonym:Collagen I; Collagen Type I; COL1A1; COL1A2; Alpha 1 type I collagen; Alpha 2 type I collagen; collagen, type I, alpha 2; OI4; collagen alpha-2(I) chain; OTTHUMP00000192906; type I procollagen; alpha 2(I)-collagen; alpha-2 type I collagen; collagen I, alpha-2 polypeptide; collagen of skin, tendon and bone, alpha-2 chain; osteogenesis imperfecta type IV; alpha-2 collagen type I;Background:Collagen is a group of naturally occurring proteins found in animals, especially in the flesh and connective tissues of mammals. It is the main component of connective tissue, and is the most abundant protein in mammals, making up about 25% to 35% of the whole-body protein content. Collagen, in the form of elongated fibrils, is mostly found in fibrous tissues such as tendon, ligament and skin, and is also abundant in cornea, cartilage, bone, blood vessels, the gut, and intervertebral disc. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.;Description:Rabbit Anti-Bovine Collagen I Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Bovine;Isotype:IgG1;Application:ELISA, IFA, RIA;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;