Cat#:PA-4240F;Product Name:Rabbit Anti-4,5-Dihydroxytryptamine Antibody;Synonym:4,5-Dihydroxytryptamine; 4,5-DHT;Background:Dihydroxytryptamine (DHT) is a neurotoxin used to selectively kill serotonergic neurons in scientific research, in the same way that 6-hydroxydopamine (6-OHDA) is used to kill dopaminergic cells. It is a synthetic amino acid which acts as a selective and irreversible inhibitor of tryptophan hydroxylase, which is a rate-limiting enzyme in the biosynthesis of serotonin.[1] Fenclonine consequently depletes serotonin in the body and reduces its actions, acting as an indirect serotonin antagonist. It is used in scientific research to investigate the effects of serotonin depletion on behaviour.;Description:Rabbit Anti-4,5-Dihydroxytryptamine Polyclonal Antibody;Host Species:Rabbit;Species Reactivity:Human;Isotype:IgM, kappa ;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
Dihydroxytryptamine (DHT) is a neurotoxin used to selectively kill serotonergic neurons in scientific research, in the same way that 6-hydroxydopamine (6-OHDA) is used to kill dopaminergic cells. It is a synthetic amino acid which acts as a selective and irreversible inhibitor of tryptophan hydroxylase, which is a rate-limiting enzyme in the biosynthesis of serotonin.[1] Fenclonine consequently depletes serotonin in the body and reduces its actions, acting as an indirect serotonin antagonist. It is used in scientific research to investigate the effects of serotonin depletion on behaviour.