Cat#:PA-4052F;Product Name:Mouse Anti-Placental Alkaline Phosphatase Antibody;Synonym:Alkaline phosphomonoesterase; ALPI; Glycerophosphatase; IAP; Intestinal alkaline phosphatase; Kasahara isozyme; EC 3.1.3.1; IAP; AP; ALP 1; ALP; ALP I; ALP L; ALP P; ALPG; ALPL; ALPP; ALPPL; ALPPL2; AP TNAP; Alk_phosphatase; alkaline phosphatase, intestinal; alkaline phosphatase; phosphomonoesterase; glycerophosphatase; alkaline phosphohydrolase; alkaline phenyl phosphatase; orthophosphoric-monoester phosphohydrolase (alkaline optimum); phosphate-monoester phosphohydrolase (alkaline optimum); Alkaline Phos.;Background:Alkaline phosphatase (ALP, ALKP) (EC 3.1.3.1) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is called dephosphorylation. As the name suggests, alkaline phosphatases are most effective in an alkaline environment. It is sometimes used synonymously as basic phosphatase. Alkaline phosphatase (ALP) removes phosphate groups from the 5' end of DNA and RNA, and from proteins, at high pH. Most mammals have 4 different isozymes: placental, placental like, intestinal and non tissue specific (found in liver, kidney and bone). Tissues with particularly high concentrations of ALP include the liver, bile ducts, placenta, and bone. Damaged or diseased tissue releases enzymes into the blood, so serum ALP measurements can be abnormal in many conditions, including bone disease and liver disease.;Description:Mouse Anti-Placental Alkaline Phosphatase Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:8C7;Isotype:IgG2a;Application:WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;