Cat#:PA-1162F;Product Name:Mouse Anti-Neurofilament Antibody;Synonym:Neurofilament; NEFL; NFL; NF-L; NF68; CMT1F; CMT2E; neurofilament, light polypeptide; 68 kDa neurofilament protein; Neurofilament triplet L protein;Background:Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.;Description:Mouse Anti-Neurofilament Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:2F22;Isotype:IgG1, kappa;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
Neurofilament; NEFL; NFL; NF-L; NF68; CMT1F; CMT2E; neurofilament, light polypeptide; 68 kDa neurofilament protein; Neurofilament triplet L protein
Gene Introduction:
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
Description:
Mouse Anti-Neurofilament Monoclonal Antibody
Host Species:
Mouse
Species Reactivity:
Human
Clone#:
2F22
Isotype:
IgG1, kappa
Application:
IHC
Usage:
For Lab Research Use Only
Storage:
Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles