Cat#:PA-1697F;Product Name:Mouse Anti-Insulin / Proinsulin Antibody;Synonym:MGC159719; INS; insulin; ILPR; IRDN; IDDM2; MODY10; proinsulin; OTTHUMP00000011161; OTTHUMP00000011162; OTTHUMP00000196036; OTTHUMP00000196038; OTTHUMP00000217519; Insulin B chain; Insulin A chain; Proinsulin; C peptide; Matrix metalloproteinase-3; transin-1; proteoglycanase; Transin-1; EC 3.4.24.17; OTTHUMP00000045949;Background:Proinsulin C-peptide It serves as an important linker between the A- and the B- chains of insulin and facilitates the efficient assembly, folding, and processing of insulin in the endoplasmic reticulum. Equimolar amounts of C-peptide and insulin are then stored in secretory granules of the pancreatic beta cells and both are eventually released to the portal circulation. Initially, the sole interest in C-peptide was as a marker of insulin secretion and has as such been of great value in furthering the understanding of the pathophysiology of type 1 and type 2 diabetes. The first documented use of the C-peptide test was in 1972. During the past decade, however, C-peptide has been found to be a bioactive peptide in its own right, with effects on microvascular blood flow and tissue health.;Description:Mouse Anti-Insulin/Proinsulin Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:D6D5;Isotype:IgG1,k;Application:ELISA, IHC, Pr, RIA;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;