Cat#:PA-071F;Product Name:Mouse Anti-Human VTN Antibody;Synonym:VTN; vitronectin; VN; V75; VNT; vitronectin (serum spreading factor, somatomedin B, complement S-protein); complement S-protein; serum spreading factor; somatomedin B; Vitronectin; S-protein; Serum-spreading factor; Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin-B; vitronectin; epibolin; OTTHUMP00000163323;Background:Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity. Vitronectin also known as VTN is a protein that in humans is encoded by the VTN gene. The protein encoded by this gene is a member of the pexin family. Vitronectin is an abundant glycoprotein found in serum and the extracellular matrix and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. Vitronectin has been speculated to be involved in hemostasis and tumor malignancy.;Description:Mouse Anti-Human VTN Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:2E946;Isotype:IgG1,k;Application:ELISA, WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;