Cat#:PA-397F;Product Name:Mouse Anti-Human TAP2 Antibody;Synonym:TAP2; transporter 2, ATP-binding cassette, sub-family B (MDR/TAP); APT2; PSF2; ABC18; ABCB3; RING11; D6S217E; antigen peptide transporter 2; PSF-2; OTTHUMP00000029078; OTTHUMP00000218770; ABC transporter, MHC 2; peptide supply factor 2; peptide transporter TAP2; really interesting new gene 11 protein; peptide transporter involved in antigen processing 2;Background:The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease.;Description:Mouse Anti-Human TAP2 Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:B487N;Isotype:IgG2b;Application:WB, IP, ICC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;