Cat#:PA-614F;Product Name:Mouse Anti-Human Syndecan 1 Antibody, RPE-Conjugated;Synonym:SDC1; SDC; CD138; SYND1; syndecan; syndecan-1; syndecan proteoglycan 1; Syndecan-1; OTTHUMP00000115942; heparan sulfate proteoglycan fibroblast growth factor receptor; CD138 antigen;Background:The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.;Description:Mouse Anti-Human Syndecan 1 Monoclonal Antibody, RPE-Conjugated;Host Species:Mouse;Species Reactivity:Human;Clone#:MI26;Isotype:IgG1, kappa;Application:FCM;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.