Cat#:PA-471F;Product Name:Mouse Anti-Human Sialophorin Antibody, FITC-Conjugated;Synonym:SPN; Sialophorin; LSN; CD43; GPL115; Leukosialin; GALGP; OTTHUMP00000123397; OTTHUMP00000196610; galactoglycoprotein; leukocyte sialoglycoprotein; sialophorin (leukosialin, CD43); sialophorin (gpL115, leukosialin, CD43);Background:SPN is a human heavily O-glycosylated transmembrane protein, which is expressed by T cells and myeloid lineage cells. Reactivity with plasma cells has been observed. The molecule is known to be defective in the Wiskott-Aldrich syndrome and may participate in T-cell activation. Immunoblotting studies have revealed molecular mass heterogeneity displayed by the antigen extracted from white blood cells of different lineage. Thus, two major bands of 140 and 130 kDa are seen for the promyelocytic cell line HL60, 110 kDa for the myeloblast cell line KG1 and a major 115 kDa band for peripheral blood lymphocytes.;Description:Mouse Anti-Human Sialophorin Monoclonal Antibody, FITC-Conjugated;Host Species:Mouse;Species Reactivity:Human;Clone#:DF-U2;Isotype:IgG1, kappa;Application:FCM;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
SPN is a human heavily O-glycosylated transmembrane protein, which is expressed by T cells and myeloid lineage cells. Reactivity with plasma cells has been observed. The molecule is known to be defective in the Wiskott-Aldrich syndrome and may participate in T-cell activation. Immunoblotting studies have revealed molecular mass heterogeneity displayed by the antigen extracted from white blood cells of different lineage. Thus, two major bands of 140 and 130 kDa are seen for the promyelocytic cell line HL60, 110 kDa for the myeloblast cell line KG1 and a major 115 kDa band for peripheral blood lymphocytes.