Cat#:PA-832F;Product Name:Mouse Anti-Human PRF1 Antibody;Synonym:perforin 1 (pore forming protein); P1; PFP; FLH2; PFN1; HPLH2; MGC65093; PRF1; perforin-1; cytolysin; lymphocyte pore-forming protein; Cytolysin; lymphocyte pore forming protein; OTTHUMP00000019759;Background:The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9,this protein creates transmembrane tubules and is caMAble of lysing non-specifically a variety of target cells. Thisprotein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule forT-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocyticlymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternativesplicing results in multiple transcript variants encoding the same protein.;Description:Mouse Anti-Human PRF1 Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:4F5;Isotype:IgG2a;Application:ELISA, FCM;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;