Cat#:PA-849F;Product Name:Mouse Anti-Human POMC Antibody;Synonym:POMC; pro-opiomelanocortin; proopiomelanocortin; beta-LPH; beta-MSH; alpha-MSH; gamma-LPH; beta-endorphin; met-enkephalin; lipotropin beta; lipotropin gamma; melanotropin beta; melanotropin alpha; melanotropin gamma; pro-ACTH-endorphin; adrenocorticotropin; corticotropin-lipotropin; adrenocorticotropic hormone; proopiomelanocortin preproprotein; beta-melanocyte-stimulating hormone; corticotropin-like intermediary peptide;Background:This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products.;Description:Mouse Anti-Human POMC Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:02B4;Isotype:IgG1, kappa;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;