Cat#:PA-979F;Product Name:Mouse Anti-Human PDCD6IP Antibody;Synonym:PDCD6IP; programmed cell death 6 interacting protein; AIP1; Alix; HP95; DRIP4; MGC17003; OTTHUMP00000161316; PDCD6-interacting protein; ALG-2 interacting protein 1; ALG-2 interacting protein X; dopamine receptor interacting protein 4; apoptosis-linked gene 2-interacting protein X;Background:This gene encodes a protein thought to participate in programmed cell death. Studies using Mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death.;Description:Mouse Anti-Human PDCD6IP Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:B235N;Isotype:IgG1;Application:ELISA, WB, IHC, IFA, IP;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
PDCD6IP; programmed cell death 6 interacting protein; AIP1; Alix; HP95; DRIP4; MGC17003; OTTHUMP00000161316; PDCD6-interacting protein; ALG-2 interacting protein 1; ALG-2 interacting protein X; dopamine receptor interacting protein 4; apoptosis-linked gene 2-interacting protein X
Gene Introduction:
This gene encodes a protein thought to participate in programmed cell death. Studies using Mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death.
Description:
Mouse Anti-Human PDCD6IP Monoclonal Antibody
Host Species:
Mouse
Species Reactivity:
Human
Clone#:
B235N
Isotype:
IgG1
Application:
ELISA, WB, IHC, IFA, IP
Usage:
For Lab Research Use Only
Storage:
Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles