Cat#:PA-1100F;Product Name:Mouse Anti-Human NPPB (N-terminal) Antibody;Synonym:natriuretic peptides B; OTTHUMP00000002506; natriuretic protein; brain type natriuretic peptide; gamma-brain natriuretic peptide; natriuretic peptide precursor B; BNP; NPPB; natriuretic peptide B; BNP-32; natriuretic peptides B;Background:This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.;Description:Mouse Anti-Human NPPB (N-terminal) Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:29G0;Isotype:IgG2a;Application:ELISA, WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;