Cat#:PA-1159F;Product Name:Mouse Anti-Human Neurofilament Protein Antibody;Synonym:150kDa medium; 160 kDa neurofilament protein; 200 kDa neurofilament protein; 68 kDa neurofilament protein; AI847934; CMT1F; CMT2E; FLJ53642; Micro glutamic acid-rich protein; mKIAA0845; Nef3; Nefm; Neurofilament 3; Neurofilament heavy polypeptide 200kDa; Neurofilament heavy polypeptide; Neurofilament light polypeptide 68kDa; Neurofilament light polypeptide; Neurofilament medium polypeptide 150kDa; Neurofilament medium polypeptide; Neurofilament protein heavy polypeptide; Neurofilament protein light chain; Neurofilament protein light polypeptide; Neurofilament protein medium polypeptide; Neurofilament triplet H protein; Neurofilament triplet L protein; Neurofilament triplet M protein; NF-H; NF-L; NF-M; NF160; NF165; NF200; NF68; NFH; NFL; NFM;Background:Neurofilaments (NFs) belong to the family of intermediate filaments (IFs) and are structural elements of the neuronal cytoskeleton in an interconnection with actin microfilaments, microtubules and other IFs. NFs are composed of three different subunits that are different, but related proteins: NF-L (70 kDa), NF-M (150-160 kDa) and NF-H (200 kDa). The antigenic determinants of each of the subunits may be unique or shared and each NF subunit is a separate gene product. During embryonic neurogenesis, the NF-L and NF-M subunits are coexpressed, whereas the activation of the NF-H subunit is delayed to the postnatal period. NF-M and NF-H subunits are unable to selfassemble and, typically, form co-polymers with NF-L.;Description:Mouse Anti-Human Neurofilament Protein Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:2F22;Isotype:IgG1, kappa;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;