Cat#:PA-1207F;Product Name:Mouse Anti-Human Myogenic Differentiation 1 Antibody;Synonym:MYOD1; myogenic differentiation 1; PUM; MYF3; MYOD; bHLHc1; myogenic factor 3; myoblast determination protein; myoblast determination protein 1; Myf-3; Myogenic factor 3; Myoblast determination protein 1;Background:The MyoD1 gene belongs to a family of myogenic determination genes, including myogenin, myf-5 and MRF4, all of which encodetranscription factors. Transfection of MyoD1 cDNA into non-muscle cells has been shown to activate expression of muscle specific genesand in some cases induce myogenesis. The MyoD1 protein is a 45 kD nuclear phosphoprotein which induces myogenesis throughtranscriptional activation of muscle-specific genes. Nuclear expression of MyoD1 is restricted to skeletal muscle tissue and has beendemonstrated to be a sensitive marker of myogenic differentiation.;Description:Mouse Anti-Human Myogenic Differentiation 1 Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:5.9B;Isotype:IgG1, kappa;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;