Cat#:PA-1375F;Product Name:Mouse Anti-Human Mammaglobin Antibody;Synonym:MGA; Mam-1A5; Mammaglobin;Background:Mammaglobin is a 93 amino acid protein with homology to other secretoglobin-uteroglobin family members that was originally identified in studies of differentially expressed cDNAs from breast carcinoma cell lines. Mammaglobin expression has also been reported in a series of malignant and nonmalignant tissues derived from the female genital tract by RT-PCR. Expression of the mammaglobin gene and protein have been demonstrated in neoplastic breast tissues and in a subset of normal breast epithelial cells within the acini of type I and type II lobules and within the columnar cells of terminal ducts. Mammaglobin expression has been found in well, moderately, and poorly differentiated invasive ductal carcinomas by IHC and in metastatic and occult breast carcinoma by RT-PCR. Mammaglobin expression is highly restricted to breast tissue and not detected in the majority of normal tissue types evaluated, with the exception of skin.;Description:Mouse Anti-Human Mammaglobin Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:304-1B6;Isotype:IgG1, kappa;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
Mammaglobin is a 93 amino acid protein with homology to other secretoglobin-uteroglobin family members that was originally identified in studies of differentially expressed cDNAs from breast carcinoma cell lines. Mammaglobin expression has also been reported in a series of malignant and nonmalignant tissues derived from the female genital tract by RT-PCR. Expression of the mammaglobin gene and protein have been demonstrated in neoplastic breast tissues and in a subset of normal breast epithelial cells within the acini of type I and type II lobules and within the columnar cells of terminal ducts. Mammaglobin expression has been found in well, moderately, and poorly differentiated invasive ductal carcinomas by IHC and in metastatic and occult breast carcinoma by RT-PCR. Mammaglobin expression is highly restricted to breast tissue and not detected in the majority of normal tissue types evaluated, with the exception of skin.
Description:
Mouse Anti-Human Mammaglobin Monoclonal Antibody
Host Species:
Mouse
Species Reactivity:
Human
Clone#:
304-1B6
Isotype:
IgG1, kappa
Application:
IHC
Usage:
For Lab Research Use Only
Storage:
Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles