Cat#:PA-1511F;Product Name:Mouse Anti-Human Lipoprotein, Low Density (LDL) Antibody;Synonym:Alpha-2-macroglobulin receptor; Apolipoprotein E receptor; LRP-1; CD91 antigen; APR; LRP; low density lipoprotein receptor-related protein 1; A2MR; CD91; APOER; TGFBR5; IGFBP3R; FLJ16451; MGC88725; LRP1; prolow-density lipoprotein receptor-related protein 1; LRP-1; type V tgf-beta receptor; LRP-85; LRP-515; LRPICD; TbetaR-V/LRP-1/IGFBP-3 receptor;Background:The protein encoded by this gene is an endocytic receptor involved in several cellular processes, includingintracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein isnecessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component ofamyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lowerthan controls in brain tissue from Alzheimer patients.;Description:Mouse Anti-Human Lipoprotein, Low Density (LDL) Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:M-45;Isotype:IgG2a;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;