Cat#:PA-2852F;Product Name:Mouse Anti-Human Filamin Antibody;Synonym:Actin-binding protein; filamin; Human Filamin; Filamins;Background:Actin-binding protein, or filamin, is a 280-kD protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and participates in the anchoring of membrane proteins for the actin cytoskeleton. Remodeling of the cytoskeleton is central to the modulation of cell shape and migration. Filamin A, encoded by the FLNA gene, is a widely expressed protein that regulates reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and second messengers.;Description:Mouse Anti-Human Filamin Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:PM6/328;Isotype:IgG1;Application:IHC, WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
Actin-binding protein; filamin; Human Filamin; Filamins
Gene Introduction:
Actin-binding protein, or filamin, is a 280-kD protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and participates in the anchoring of membrane proteins for the actin cytoskeleton. Remodeling of the cytoskeleton is central to the modulation of cell shape and migration. Filamin A, encoded by the FLNA gene, is a widely expressed protein that regulates reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and second messengers.
Description:
Mouse Anti-Human Filamin Monoclonal Antibody
Host Species:
Mouse
Species Reactivity:
Human
Clone#:
PM6/328
Isotype:
IgG1
Application:
IHC, WB
Usage:
For Lab Research Use Only
Storage:
Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles