Cat#:PA-1245F;Product Name:Mouse Anti-Human Epithelial Membrane Ag MUC1 Antibody;Synonym:EMA; PEM; PUM; KL-6; MAM6; PEMT; CD227; H23AG; MUC-1; MUC-1/X; MUC1/ZD; MUC-1/SEC; MUC1; mucin-1; episialin; DF3 antigen; H23 antigen; OTTHUMP00000033786; OTTHUMP00000033787; OTTHUMP00000033788; OTTHUMP00000033789; OTTHUMP00000033790; OTTHUMP00000033791; OTTHUMP00000033792; OTTHUMP00000033793; OTTHUMP00000033794; OTTHUMP00000033795; mucin 1, transmembrane; tumor-associated mucin; carcinoma-associated mucin; polymorphic epithelial mucin; peanut-reactive urinary mucin; tumor associated epithelial mucin; breast carcinoma-associated antigen DF3; tumor-associated epithelial membrane antigen; mucin 1, cell surface associated; PEM; PUM; CD227; mucin 1, transmembrane; Breast carcinoma-associated antigen DF3; Carcinoma-associated mucin; Peanut-reactive urinary mucin; Polymorphic epithelial mucin; Tumor-associated epithelial membrane antigen; Tumor-associated mucin; MUC-1/S; OTTHUMP000000337862; OTTHUMP000000337882; OTTHUMP000000337892; OTTHUMP000000337932; CD227 antigen;Background:This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.;Description:Mouse Anti-Human Epithelial Membrane Ag MUC1 Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:M10H5;Isotype:IgG;Application:ELISA, Pr;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.
Description:
Mouse Anti-Human Epithelial Membrane Ag MUC1 Monoclonal Antibody
Host Species:
Mouse
Species Reactivity:
Human
Clone#:
M10H5
Isotype:
IgG
Application:
ELISA, Pr
Usage:
For Lab Research Use Only
Storage:
Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles