Cat#:PA-3197F;Product Name:Mouse Anti-Human Deoxynucleotidyltransferase, Terminal Antibody, FITC-Conjugated;Synonym:DNTT; TDT; DNA nucleotidylexotransferase; OTTHUMP00000020171; terminal transferase; terminal addition enzyme; terminal deoxynucleotidyltransferase; EC=2.7.7.31; terminal deoxyribonucleotidyltransferase; nucleosidetriphosphate: DNA deoxynucleotidylexotransferase; deoxynucleotidyltransferase, terminal; EC 2.7.7; EC 2.7.7.31;Background:TdT is a 58 kDa protein that catalyses the polymerisation of deoxynucleotides on the 3’ hydroxyl end of a polydeoxynucleotide without template instructions. TdT is present in the nuclei of normal T and B lymphocyte precursors and the neoplastic equivalent. Positive cells are present in normal thymus, and in few normal bone marrow cells, corresponding to hemapoietic precursors. Most cases of ALL are TdT positive, 37 % of AML cases are TdT positive.;Description:Mouse Anti-Human Deoxynucleotidyltransferase, Terminal Monoclonal Antibody, FITC-Conjugated;Host Species:Mouse;Species Reactivity:Human;Clone#:HT-7;Isotype:IgG1, kappa;Application:FCM;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
TdT is a 58 kDa protein that catalyses the polymerisation of deoxynucleotides on the 3’ hydroxyl end of a polydeoxynucleotide without template instructions. TdT is present in the nuclei of normal T and B lymphocyte precursors and the neoplastic equivalent. Positive cells are present in normal thymus, and in few normal bone marrow cells, corresponding to hemapoietic precursors. Most cases of ALL are TdT positive, 37 % of AML cases are TdT positive.