Cat#:PA-3556F;Product Name:Mouse Anti-Human CD5 Antibody;Synonym:CD5; LEU1; T1; T-cell surface glycoprotein CD5; OTTHUMP00000236973; CD5 antigen (p56-62); lymphocyte antigen T1/Leu-1;Background:CD5 is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells, and also on T cells.[1] B-1 cells have limited diversity of their B-cell receptor due to their lack of the enzyme terminal deoxynucleotidyl transferase (TdT) and are potentially self-reactive. CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by very strong stimuli (such as bacterial proteins) and not by normal tissue proteins. CD5 was used as a T-cell marker until Monoclonal antibodies against CD3 were developed. In humans, the gene is located on the long arm of chromosome 11.;Description:Mouse Anti-Human CD5 Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:UCHT-4;Isotype:IgG1;Application:EIA;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;