Cat#:PA-3551F;Product Name:Mouse Anti-Human CD59 Antibody;Synonym:CD59 glycoprotein; protectin; 1F5 antigen; MEM43 antigen; Ly-6-like protein; OTTHUMP00000232408; OTTHUMP00000232409; OTTHUMP00000232410; OTTHUMP00000232411; OTTHUMP00000232412; OTTHUMP00000232413; OTTHUMP00000232414; OTTHUMP00000232415; OTTHUMP00000232416; OTTHUMP00000232608; OTTHUMP00000232610; T cell-activating protein; human leukocyte antigen MIC11; lymphocytic antigen CD59/MEM43; 20 kDa homologous restriction factor; membrane attack complex (MAC) inhibition factor; surface anitgen recognized by Monoclonal 16.3A5; CD59 antigen p18-20 (antigen identified by Monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344); Membrane inhibitor of reactive lysis; Membrane attack complex inhibition factor; CD59 antigen, complement regulatory protein; MEM43; MAC-inhibitory protein; Protectin; CD59 antigen; CD59 molecule, complement regulatory protein; 1F5; EJ16; EJ30; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF20; MACIF; MIC11; MSK21; 16.3A5; HRF-20; MAC-IP; p18-20; MGC2354; FLJ38134; FLJ92039; CD59;Background:This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.;Description:Mouse Anti-Human CD59 Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:MEM-54;Isotype:IgG2a;Application:FCM, IP;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;

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Mouse Anti-Human CD59 Antibody Online Inquiry

Cat#:
PA-3551F

Product Name:
Mouse Anti-Human CD59 Antibody

Synonym:
CD59 glycoprotein; protectin; 1F5 antigen; MEM43 antigen; Ly-6-like protein; OTTHUMP00000232408; OTTHUMP00000232409; OTTHUMP00000232410; OTTHUMP00000232411; OTTHUMP00000232412; OTTHUMP00000232413; OTTHUMP00000232414; OTTHUMP00000232415; OTTHUMP00000232416; OTTHUMP00000232608; OTTHUMP00000232610; T cell-activating protein; human leukocyte antigen MIC11; lymphocytic antigen CD59/MEM43; 20 kDa homologous restriction factor; membrane attack complex (MAC) inhibition factor; surface anitgen recognized by Monoclonal 16.3A5; CD59 antigen p18-20 (antigen identified by Monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344); Membrane inhibitor of reactive lysis; Membrane attack complex inhibition factor; CD59 antigen, complement regulatory protein; MEM43; MAC-inhibitory protein; Protectin; CD59 antigen; CD59 molecule, complement regulatory protein; 1F5; EJ16; EJ30; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF20; MACIF; MIC11; MSK21; 16.3A5; HRF-20; MAC-IP; p18-20; MGC2354; FLJ38134; FLJ92039; CD59

Gene Introduction:
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.