Cat#:PA-3574F;Product Name:Mouse Anti-Human CD4 MonoclonalAntibody, FITC-Conjugated;Synonym:CD4; CD4 molecule; CD4 antigen; CD4mut; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); OTTHUMP00000238897; T-cell surface antigen T4/Leu-3;Background:CD4 is a 55 kDa glycoprotein with four immunoglobulin-like external domains, a transmembrane domain and a highly conserved intracellular domain. CD4 acts as a coreceptor in MHC class II-restricted antigen-induced T-cell activation. Further, CD4 has a role in the regulation of T-B lymphocyte adhesion in the absence of antigen recognition, and in thymic differentiation. CD4 is expressed on thymocyte subsets, it marks helper/inducer T cells, and it is expressed in 55-65% of mature peripheral T cells. Subpopulations of suppressor or cytotoxic T cells can be identified among CD4-positive T cells. CD4 is also expressed on monocytes/macrophages, Langerhans cells and other dendritic cells. CD4 is not expressed on B cells.The majority of peripheral T-cell lymphomas are derived from the helper T-cell subset, so most postthymic T-cell neoplasms are CD4-positive.;Description:Mouse Anti-Human CD4 MonoclonalAntibody, FITC-Conjugated;Host Species:Mouse;Species Reactivity:Human;Clone#:MT321;Isotype:IgG1, kappa;Application:FCM;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;