Cat#:PA-1665F;Product Name:Mouse Anti-Human CD41 Antibody;Synonym:integrin alpha-IIb; GPalpha IIb; platelet-specific antigen BAK; platelet fibrinogen receptor, alpha subunit; Platelet membrane glycoprotein IIb; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B); CD41 antigen; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); GTA; CD41; GP2B; HPA3; CD41B; GPIIb; ITGA2B;Background:ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.;Description:Mouse Anti-Human CD41 Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:M150;Isotype:IgG1;Application:EIA, LF;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;