Cat#:PA-3595F;Product Name:Mouse Anti-Human CD3 MonoclonalAntibody, APC-Conjugated;Synonym:4930549J05Rik; A430104F18Rik; AW552088; Cd247; CD247; CD247 antigen, zeta subunit; CD247 molecule; CD3; CD3 delta; CD3 epsilon; CD3 eta; 3 gamma; CD3 molecule delta polypeptide; CD3 molecule, epsilon polypeptide; CD3 molecule, gamma polypeptide; CD3 zeta; CD3d; CD3D antigen delta polypeptide; CD3d antigen, delta polypeptide (TiT3 complex); CD3d molecule delta; CD3d molecule delta CD3 TCR complex; CD3d molecule, delta (CD3-TCR complex); CD3e antigen; CD3E; CD3E antigen epsilon polypeptide; CD3e antigen, epsilon polypeptide (TiT3 complex); CD3e molecule epsilon; CD3e molecule epsilon CD3 TCR complex; CD3e molecule, epsilon (CD3-TCR complex); CD3epsilon; CD3G; CD3g antigen; CD3G antigen gamma polypeptide; D3g antigen, gamma polypeptide (TiT3 complex); CD3g molecule gamma; CD3g molecule gamma CD3 TCR complex; CD3g molecule, gamma (CD3-TCR complex); CD3Q; CD3Z; CD3zeta; Ctg3; FLJ17620; LJ17664; FLJ18683; FLJ79544; FLJ94613; MGC138597; OKT3, delta chain; TTHUMP00000032544; T cell receptor; T cell receptor T3 delta chain; T cell receptor T3 gamma chain; T cell receptor T3 zeta chain; T cell receptor zeta chain; T cell surface glycoprotein CD3; T cell surface glycoprotein CD3 delta chain; T cell surface glycoprotein CD3 epsilon chain; T cell surface glycoprotein CD3 gamma chain; T cell surface glycoprotein CD3 zeta chain; T-cell antigen receptor complex, epsilon subunit of T3; T-cell antigen receptor complex, gamma subunit of T3 T-cell antigen receptor complex, zeta subunit of CD3 T-cell receptor T3 delta chain; T-cell receptor T3 gamma chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 delta chain; T-cell surface glycoprotein CD3 gamma chain; T3d; T3e; T3g; T3z; TCRE; TCRk; Tcrz; TCRzeta;Background:Human TCR/CD3 is a complex structure on the lymphocyte surface. It consists of the TCRαβ or TCRγδ heterodimer and the associated CD3 complex. The CD3 complex is composed of six polypeptides with usually four different transmembrane CD3 chains, γ (gamma), δ(delta), ε (epsilon), and ζ(zeta). Three different dimers, γε, δε, and ζζ, constitute the CD3 complex. The Mr of CD3ε is 20000.CD3 is first detectable in early thymocytes and its appearance probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, during early stages of maturation, the CD3 antigen is predominantly present in the cell cytoplasm. In medullary thymocytes, the CD3 antigen is predominantly detected on the cell surface.Anti-CD3, UCHT1, was included in the First and Third International Workshops and Conferences on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with theCD3 antigen. Anti-CD3, UCHT1, reacts with the 20 kDa e-chain of CD3.;Description:Mouse Anti-Human CD3 MonoclonalAntibody, APC-Conjugated;Host Species:Mouse;Species Reactivity:Human;Clone#:UCHU2;Isotype:IgG1, kappa;Application:FCM;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
Human TCR/CD3 is a complex structure on the lymphocyte surface. It consists of the TCRαβ or TCRγδ heterodimer and the associated CD3 complex. The CD3 complex is composed of six polypeptides with usually four different transmembrane CD3 chains, γ (gamma), δ(delta), ε (epsilon), and ζ(zeta). Three different dimers, γε, δε, and ζζ, constitute the CD3 complex. The Mr of CD3ε is 20000.CD3 is first detectable in early thymocytes and its appearance probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, during early stages of maturation, the CD3 antigen is predominantly present in the cell cytoplasm. In medullary thymocytes, the CD3 antigen is predominantly detected on the cell surface.Anti-CD3, UCHT1, was included in the First and Third International Workshops and Conferences on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with theCD3 antigen. Anti-CD3, UCHT1, reacts with the 20 kDa e-chain of CD3.