Cat#:PA-3590F;Product Name:Mouse Anti-Human CD33 Molecule Antibody, RPE-Conjugated;Synonym:CD33; CD33 molecule; p67; SIGLEC3; FLJ00391; SIGLEC-3; SIGLEC3; myeloid cell surface antigen CD33; gp67; CD33 antigen (gp67); sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3;Background:CD33 is a member of the siglec family (sialic acid binding immunoglobulin-like lectins) referred to as Siglec-3. It is the smallest member of the siglec family having a molecular weight of 67 kDa. CD33 mediates protein-carbohydrate cellular interactions in addition to protein-protein recognition. The CD33 gene is located on chromosome 19. CD33 is expressed by subsets of monocytes and neutrophils. Committed hemapoietic progenitors, including multipotential stem cells (CFU-GEMM) and precursors of granulocytes and macrophages (CFU-GM) and early erythroid progenitors (BFU-E) express CD33. The antigen has been found on the cell surface of leukaemic blasts from the vast majority of cases of AML, including megakaryoblastic, but not erythroblastic variants. Leukaemic lymphoblasts do not show any expression of CD33.;Description:Mouse Anti-Human CD33 Molecule Monoclonal Antibody, RPE-Conjugated;Host Species:Mouse;Species Reactivity:Human;Clone#:WM-65;Isotype:IgG1, kappa;Application:FCM;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;