Cat#:PA-3092F;Product Name:Mouse Anti-Human CD105 Antibody;Synonym:CD105 antigen; Osler-Rendu-Weber syndrome 1; endoglin; END; ORW; HHT1; ORW1; CD105; FLJ41744; ENG; OTTHUMP00000022221; OTTHUMP00000022222;Background:This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.;Description:Mouse Anti-Human CD105 Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:MEM-237;Isotype:IgG2a;Application:WB, FCM, IP;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Description:
Mouse Anti-Human CD105 Monoclonal Antibody
Host Species:
Mouse
Species Reactivity:
Human
Clone#:
MEM-237
Isotype:
IgG2a
Application:
WB, FCM, IP
Usage:
For Lab Research Use Only
Storage:
Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles