Mouse Anti-Human C5b-9 Antibody Online Inquiry

• Cat#:
• PA-3734F

• Product Name:
• Mouse Anti-Human C5b-9 Antibody

• Synonym:
• C5b-9; C5b-C6-C7-C8-C9{n}; membrane attack complex (MAC); membrane attack complex; MAC

• Gene Introduction:
• Activation of the complement system plays a key role in normal inflammatory response to injury but may cause substantial injury when activated inappropriately. The complement system is activated either through the classical (antibody induced) or the alternative (microbial surface, polysacharride induced) pathway, both leading to the formation of the C5b-9 complex. Fluid-phase binding of the multifunctional glycoprotein S-protein (vitronectin) to C5b-9 leads to the formation of a cytolytically inactive complex, SC5b-9, which is unable to attach to cells (3, 4). For review of the complement system (2, 3).

• Description:
• Mouse Anti-Human C5b-9 Monoclonal Antibody

• Host Species:
• Mouse

• Species Reactivity:
• Human

• Clone#:
• aE22

• Isotype:
• IgG2a, kappa

• Application:
• IHC

• Usage:
• For Lab Research Use Only

• Storage:
• Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles

• Clonality:
• Monoclonal

• Form:
• Liquid