Cat#:PA-3820F;Product Name:Mouse Anti-Human Bromodeoxyuridine Antibody, FITC-Conjugated;Synonym:Bromodeoxyuridine; BUdr; BrdU;Background:Bromodeoxyuridine (BrdU) is a thymidine analogue, capable of being incorporated into DNA in place of thymidine during DNA synthesis.By pulse labelling with BrdU, cellular DNA synthesis can be detected with anti-BrdU antibodies. BrdU labelling is being used for the study of cell cycle kinetics in normal human cells, animal cells, solid tumors and cancer cell lines. These include CNS tumors, head and neck tumors, gastric and colorectal cancer, breast tumors, hematopoietic tumors, genitourinary tumors, renal carcinoma, bladder cancer and prostate cancer. The BrdU labelling may allow the determination of the labelling index (LI), Ts and Tpot. LI, the fraction of cells synthesizing DNA, is defined as the number of BrdU-labelled cells divided by the total number of cells analysed. Ts is the duration of the S-phase in the cell cycle. Tpot is a measure of the theoretical proliferative capacity of a tumor cell population in the absence of cell loss and is calculated from LI and Ts values.;Description:Mouse Anti-Human Bromodeoxyuridine Monoclonal Antibody, FITC-Conjugated;Host Species:Mouse;Species Reactivity:Human;Clone#:Bu21b;Isotype:IgG1, kappa.;Application:FCM;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;