Cat#:PA-3849F;Product Name:Mouse Anti-Human BCL6 Antibody;Synonym:BCL6; B-cell CLL/lymphoma 6; B-cell lymphoma 6 protein; BCL-5; BCL-6; protein LAZ-3; zinc finger protein 51; B-cell lymphoma 5 protein; B-cell lymphoma 6 protein transcript; B-cell lymphoma 6 protein transcript; cys-his2 zinc finger transcription factor; zinc finger transcription factor BCL6S; lymphoma-associated zinc finger gene on chromosome 3; OTTHUMP00000209895; OTTHUMP00000209897;Background:The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.;Description:Mouse Anti-Human BCL6 Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Rat;Clone#:PG-B7q;Isotype:IgG1, kappa;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;