Cat#:PA-2828F;Product Name:Mouse Anti-Folate Antibody;Synonym:Folate; Folic acid; Vitamin B9; 5 Methyl THFA; 5 Methyltetrahydrofolate; Tetrahydrofolate; Tetrahydrofolic acid; THFA; PTEROYLGLUTAMIC ACID; PTEROYGLUTAMIC ACID; PTEGLU; PGA; Folbal; Folcidin; Folcysteine; Foldine; foldine(france); Folettes; Foliamin; folic; folicacid(vitaminb11); Folicet; folico(italy); folina(italy); Folipac; Folsav; Foluite; Folvite; vitamin Bc; folacin;Background:Folic acid and Folate (the anion form) are forms of a water-soluble B vitamin. These occur naturally in food and can also be taken as supplements. The biologically active form of folic acid is tetrahydrofolic acid (THFA), which is derived by the 2-step reduction of folate involving dihydrofolate reductase. THFA plays a key role in the transfer of 1-carbon units (such as methyl, methylene, and formyl groups) to the essential substrates involved in the synthesis of DNA, RNA, and proteins. More specifically, THFA is involved with the enzymatic reactions necessary to synthesis of purines, thymidine, and amino acids. Manifestations of folate deficiency thereafter, not surprisingly, would involve impairment of cell division, accumulation of possibly toxic metabolites such as homocysteine, and impairment of methylation reactions involved in the regulation of gene expression, thus increasing neoplastic risks.;Description:Mouse Anti-Folate Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Bacteria;Clone#:B765G;Isotype:IgG1;Application:ELISA;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
Folic acid and Folate (the anion form) are forms of a water-soluble B vitamin. These occur naturally in food and can also be taken as supplements. The biologically active form of folic acid is tetrahydrofolic acid (THFA), which is derived by the 2-step reduction of folate involving dihydrofolate reductase. THFA plays a key role in the transfer of 1-carbon units (such as methyl, methylene, and formyl groups) to the essential substrates involved in the synthesis of DNA, RNA, and proteins. More specifically, THFA is involved with the enzymatic reactions necessary to synthesis of purines, thymidine, and amino acids. Manifestations of folate deficiency thereafter, not surprisingly, would involve impairment of cell division, accumulation of possibly toxic metabolites such as homocysteine, and impairment of methylation reactions involved in the regulation of gene expression, thus increasing neoplastic risks.
Description:
Mouse Anti-Folate Monoclonal Antibody
Host Species:
Mouse
Species Reactivity:
Bacteria
Clone#:
B765G
Isotype:
IgG1
Application:
ELISA
Usage:
For Lab Research Use Only
Storage:
Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles