Cat#:PA-3057F;Product Name:Mouse Anti-Estrogen Receptor 1 Antibody;Synonym:ESR1; estrogen receptor 1; NR3A1; ESR; Era; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1; ER; ER-alpha; DKFZp686N23123; ESRA; estrogen receptor; estrogen receptor alpha delta 3*, 4, 5, 6, 7*/819-2 isoform; estrogen receptor alpha delta 4 +49 isoform; estrogen receptor alpha delta 4*, 5, 6, 7*/654 isoform; OTTHUMP00000017718; OTTHUMP00000017719;Background:The estrogen receptor (ER) is a 66 kDa protein that mediates the actions of estrogen in estrogen-responsive tissues. It is a member of a large superfamily of nuclear-hormone receptors that function as ligand-activated transcription factors. The ER gene consists of more than 140 kb of genomic DNA divided into 8 exons. These translate into a protein with six functionally discrete domains, labeled A through F. ER [1D5] reacts with the amino-terminal domain in the A/B region of ER-alpha. This clone has been established to work in formalin-fixed, paraffin-embedded tissues and has been published in numerous breast cancer research studies.;Description:Mouse Anti-Estrogen Receptor 1 Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:1E6;Isotype:IgG1;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;