Cat#:PA-3084F;Product Name:Mouse Anti-Enolase 2 (Gamma, Neuronal) Antibody;Synonym:ENO2; enolase 2 (gamma, neuronal); NSE; gamma-enolase; neural enolase; neuron-specific enolase; neurone-specific enolase; neuron specific gamma enolase; 2-phospho-D-glycerate hydrolyase; 2-phospho-D-glycerate hydro-lyase; EC 4.2.1.11; OTTHUMP00000239836; OTTHUMP00000239837; OTTHUMP00000239839; OTTHUMP00000239840;Background:ENO2 recognizes a protein of 46 kDa, identified as neuron-specific enolase (NSE). Enolases are homo- or heterodimers of the three subunits: alpha (46 kDa), beta (44 kDa), and gamma (46 kDa). The alpha-subunit is expressed in most tissues and the beta-subunit only in muscle. The gamma-subunit is expressed primarily in neurons, in normal and in neoplastic neuroendocrine cells. NSE shows no cross-reaction with the alpha- or beta-subunits of NSE. Coexpression of NSE and chromogranin A is common in neuroendocrine neoplasms.;Description:Mouse Anti-Enolase 2 (Gamma, Neuronal) Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:BC111;Isotype:IgG1;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
ENO2 recognizes a protein of 46 kDa, identified as neuron-specific enolase (NSE). Enolases are homo- or heterodimers of the three subunits: alpha (46 kDa), beta (44 kDa), and gamma (46 kDa). The alpha-subunit is expressed in most tissues and the beta-subunit only in muscle. The gamma-subunit is expressed primarily in neurons, in normal and in neoplastic neuroendocrine cells. NSE shows no cross-reaction with the alpha- or beta-subunits of NSE. Coexpression of NSE and chromogranin A is common in neuroendocrine neoplasms.