Cat#:PA-3456F;Product Name:Mouse Anti-Chromogranin A Antibody;Synonym:CHGA; chromogranin A (parathyroid secretory protein 1); CGA; CHGA; chromogranin A; SP-I; parathyroid secretory protein 1;betagranin (N-terminal fragment of chromogranin A); chromogranin A (parathyroid secretory protein 1); vasostatin; pancreastatin; parastatin; Pituitary secretory protein;Background:Chromogranin A (CGA) is the major member of the granin family of acidic secretory glycoproteins that are expressed in all endocrine and neuroendocrine cells. Chromogranin A regulates catecholamine storage and are released through intracellular (vesiculogenic) and extracellular (catecholamine release–inhibitory) mechanisms. Chromogranin A also plays a role in targeting peptide hormones and neurotransmitters to granules of the regulated pathway by virtue of their ability to aggregate in the low-pH, high-calcium environment of the trans-Golgi network. Therefore, Chromogranin A represents a specific marker of neuroendocrine cells and tumours including pheochromocytomas.;Description:Mouse Anti-Chromogranin A Monoclonal Antibody;Host Species:Mouse;Species Reactivity:Human;Clone#:LK2H10 + PHF6;Isotype:IgG 1 + IgG 1;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;