Cat#:PA-3250F;Product Name:Mouse Anti-Catenin beta (exon 3) Antibody;Synonym:Beta catenin; Beta-catenin; Cadherin associated protein; Catenin beta 1; Catenin beta-1; CATNB; CTNB1_HUMAN; CTNNB; CTNNB1; FLJ37923; DKFZp686D02253; OTTHUMP00000209289; catenin (cadherin-associated protein), beta; FLJ25606;Background:The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene;Description:Mouse Anti-Catenin beta (exon 3) Monoclonal Antibody;Host Species:Mouse;Clone#:BDI931;Isotype:IgG1,k;Application:ELISA, ICC, IP, WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;