Cat#:PA-2901F;Product Name:Monoclonal Mouse Anti-Human Follicular Dendritic Cell;Synonym:FDC; FDCs; Follicular dendritic cell;Background:Follicular dendritic cells (FDCs) are present in primary lymphoid follicles and in the germinal centres of secondary lymphoid follicles of lymph nodes, spleen and tonsils. These cells are characterized by numerous cytoplasmic long branching processes extending between adjacent lymphoid cells that form a three-dimentional network. FDCs have important functions in the selection of memory B lymphocytes during germinal centre reactions. They present native antigens to potential memory cells, of which only B cells with high affinity B-cell receptors can bind. These B lymphocytes survive, whereas non-binding B cells undergo apoptotic cell death. The immunophysiological kinetics, developmental processes (including their cellular origin), morphological and functional transformation, terminal fate, and pathological behaviour of FDCs are still quite obscure.;Description:Monoclonal Mouse Anti-Human Follicular Dendritic Cell;Host Species:Mouse;Species Reactivity:Human;Clone#:CNA.53;Isotype:IgM;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;