Cat#:PA-1583F;Product Name:Monoclonal Mouse Anti-Human Cytokeratin 19;Synonym:K19; CK19; K1CS; MGC15366; keratin, type I cytoskeletal 19; CK-19; keratin-19; cytokeratin 19; cytokeratin-19; OTTHUMP00000164620; keratin, type I, 40-kd; 40-kDa keratin intermediate filament;Background:Cytokeratin 19 (CK 19) belongs to the intermediate filaments, which create a cytoskeleton in almost all cells. In contrast to other intermediate filaments, cytokeratins (CKs) are made up of a highly complex multigene family of polypeptides with molecular masses ranging from 40 to 68 kDa. Twenty distinct CK polypeptides have been revealed in various human epithelial cells. They can be divided into an acidic (type I) and a neutral-basic (type II) subfamily. CK 19 belongs to the acidic type of cytokeratins, and is a low molecular mass cytokeratin (40 kDa) typically expressed in simple epithelia, superficial, intermediate and basal cells of transitional epithelium as well as luminal, basal and myoepithelial cells in a few complex epithelia. CK 19 is normally not expressed in stratified squamous epithelia, but may be present in modified squamous epithelium invaded by lymphocytes as well as in basal cells in non-keratinizing stratified squamous epithelium.;Description:Monoclonal Mouse Anti-Human Cytokeratin 19;Host Species:Mouse;Species Reactivity:Human;Clone#:RCK119;Isotype:IgG1, kappa;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;