Cat#:PA-1587F;Product Name:Monoclonal Mouse Anti-Human Cytokeratin 18;Synonym:K18; CYK18; keratin, type I cytoskeletal 18; CK-18; keratin-18; cytokeratin 18; cytokeratin-18; cell proliferation-inducing protein 46; cell proliferation-inducing gene 46 protein;Background:Cytokeratin 18 belongs to the intermediate filaments, which create a cytoskeleton in almost all cells. In contrast to other intermediate filaments, cytokeratins (CKs) are made up of a highly complex multigene family of polypeptides with molecular masses ranging from 40 to 68 kDa. Until now, 20 distinct CK polypeptides have been revealed in various human epithelial cells. They can be divided into an acidic (type I) and a neutral-basic (type II) subfamily. CK 18, a 45 kDa protein, belongs to the acidic type of cytokeratins, and is typically expressed in simple, nonstratified epithelia. However, CK 18 is also expressed in basal and superficial cells of transitional epithelium as well as in the luminal/secretory cells of complex epithelia.;Description:Monoclonal Mouse Anti-Human Cytokeratin 18;Host Species:Mouse;Species Reactivity:Human;Clone#:DC 21;Isotype:IgG1, kappa;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;