Cat#:PA-3398F;Product Name:Monoclonal Mouse Anti-Cytomegalovirus;Synonym:55 kDa immediate-early protein 1; 45 kDa immediate-early protein 2; CMV; Envelope glycoprotein B; gB; Glycoprotein B; HHV 5; HHV5; Human herpesvirus 5; IE1; IE2; UL122; UL122 regulatory protein IE2; UL123; UL123 regulatory protein IE1; UL55; UL55 envelope glycoprotein B;Background:Human cytomegalovirus is a ubiquitous herpes virus. The primary infection usually occurs in childhood where it most often is asymptomatic. After initial exposure, the virus establishes a life-long infection. In neonates, and in immunocompromised individuals, such as AIDS patients and transplant recipients, HCMV can cause severe life-threatening infections, and it is the most common cause of viral birth defects. The virus retains the capability of reactivation which may occur following blood transfusions, pregnancy, solid-organ or bone marrow transplantation, immunosuppressive therapy, or other viral infections. HCMV infects leukocytes, endothelial cells, connective tissue cells and epithelial cells, and is transmitted through most bodily fluids. Members of the herpes virus family have been implicated in the etiology of several human cancers. In the case of HCMV it has been associated with cervical carcinoma, adenocarcinomas of the prostate and colon, and Kaposi’s sarcoma. HCMV infections have been shown to modulate the expression of various proteins involved in cell cycle regulation and apoptosis.;Description:Monoclonal Mouse Anti-Cytomegalovirus;Host Species:Mouse;Species Reactivity:Human;Clone#:DDG9 + CCI3;Isotype:IgG2a, kappa + IgG1, kappa;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;