Cat#:PA-1590F;Product Name:Monoclonal Mouse Anti-Cytokeratin 17;Synonym:PC; K17; PC2; PCHC1; keratin, type I cytoskeletal 17; 39.1; CK-17; keratin-17; cytokeratin-17; OTTHUMP00000164770; keratin 17 epitope S1; keratin 17 epitope S2; keratin 17 epitope S4;Background:Cytokeratin 17 belongs to the intermediate filaments, which create a cytoskeleton in almost all eukaryotic cells. In contrast to other intermediate filaments, cytokeratins (CKs) are made up of a highly complex multigene family of polypeptides with molecular masses ranging from 40 to 68 kDa. CKs are generally held to belong to the most fundamental markers of epithelial differentiation, and until now, 20 distinct CK polypeptides have been revealed in various human epithelia. The CKs can be divided into an acidic type A (class I) and a neutral-basic type B (class II) subfamily. CK 17, a 46 kDa protein, belongs to the acidic type A subfamily, and its distribution is confined to basal and myoepithelial cells of a group of complex epithelia and transitional epithelium as well as to the outer root sheet of hair folliculi.;Description:Monoclonal Mouse Anti-Cytokeratin 17;Host Species:Mouse;Species Reactivity:Human;Clone#:F4;Isotype:IgG2b, kappa;Application:IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;