Cat#:PA-961F;Product Name:Goat Anti-Fructose-6-Phosphate Kinase Antibody;Synonym:Fructose-6-Phosphate Kinase; 6 Phosphofructokinase Muscle; EC 2.7.1.11; GSD7; MGC8699; PFKA; PFKL; PFKM; PFKP; PFKX; Phosphofructo 1 Kinase Isozyme A; Phosphofructokinase 1; Phosphofructokinase M; Phosphofructokinase muscle; Phosphofructokinase muscle type; Phosphofructokinase polypeptide X; Phosphohexokinase; EC 2.7.1.11; 6-phosphofructokinase; phosphofructokinase;Background:Phosphofructokinase catalyzes the irreversible conversion of fructose 6 phosphate to fructose 1,6 bisphosphate. Mammalian PFK is a complex isozyme consisting of 3 subunits: muscle (M), liver (L), and platelet (P). Each subunit is encoded by a separate structural locus on chromosomes 1(M), 21(L), and 10(P). PFKL is the major form in liver and kidney while only M type PFK isozyme is expressed in mature muscle; therefore, muscle contains only homotetramers of M subunits. Erythrocytes contain both L and M subunits, and these randomly tetramerize to form M4, L4, and 3 additional hybrid forms of the holoenzyme.;Description:Goat Anti-Fructose-6-Phosphate Kinase Polyclonal Antibody;Host Species:Goat;Species Reactivity:Human;Isotype:IgG1, kappa;Application:ELISA, IEP;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;
Phosphofructokinase catalyzes the irreversible conversion of fructose 6 phosphate to fructose 1,6 bisphosphate. Mammalian PFK is a complex isozyme consisting of 3 subunits: muscle (M), liver (L), and platelet (P). Each subunit is encoded by a separate structural locus on chromosomes 1(M), 21(L), and 10(P). PFKL is the major form in liver and kidney while only M type PFK isozyme is expressed in mature muscle; therefore, muscle contains only homotetramers of M subunits. Erythrocytes contain both L and M subunits, and these randomly tetramerize to form M4, L4, and 3 additional hybrid forms of the holoenzyme.