Cat#:PA-4230F;Product Name:Mouse Anti-8-Hydroxyguanosine Antibody;Synonym:8-OHG; 8-OH-GUO; 8-OXO-G; 8-OXOGUANOSINE; 8-Oxo-D-guanosine; 7,8-DIHYDRO-8-OXO-GUANOSINE; 8-HYDROXYGUANOSINE;Background:8-Hydroxyguanosine is a nucleoside which is an oxidative derivative of guanosine. Measurement of the levels of 8-hydroxyguanosine is used as a biomarker of oxidative stress. 8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer’s disease;Description:Mouse Anti-8-Hydroxyguanosine Monoclonal Antibody;Formulation:Liquid Solution;Host Species:Mouse;Species Reactivity:Human;Clone#:15B4;Isotype:IgG2a;Application:ELISA, IHC;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;