Cat#:PA-4059F;Product Name:Rabbit Anti-Human ANAPC2 (C-terminal)Antibody;Synonym:ANAPC2; anaphase promoting complex subunit 2; APC2; RP11-350O14.5; Anaphase-promoting complex subunit 2; APC2; Cyclosome subunit 2; KIAA1406; anaphase-promoting complex subunit 2; cyclosome subunit 2; OTHUMP00000022692;Background:A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation.;Description:Rabbit Anti-Human ANAPC2 (C-terminal)Polyclonal Antibody;Formulation:Liquid Solution;Host Species:Rabbit;Species Reactivity:Human;Isotype:IgG2b;Application:ELISA, IP, WB;Storage:Store antibody products at 2-8°C. For long term storage, aliquot and freeze at -20°C. Avoid repeated freeze/thaw cycles;Usage:For Lab Research Use Only;